Off-label use for hyperbilirubinemia: Phenobarbital induces glucuronyl transferase and hepatic bilirubin-binding Y-protein to decrease serum bilirubin concentrationsObserve Intently (one)somatropin will minimize the extent or outcome of phenobarbital by influencing hepatic/intestinal enzyme CYP3A4 metabolism.In smaller doses, the barbiturates may w